LIFE Description — aTyr Pharma Inc
aTyr Pharma is engaged in the discovery and clinical development of medicines for patients suffering from severe, rare diseases, using its knowledge of Physiocrine biology. Co. has discovered about 300 Physiocrines (physio for life and crine for specific activity), a class of naturally occurring proteins that promote homeostasis, a process of restoring stressed or diseased tissue to a healthier state. Physiocrines are extracellular signaling regions of tRNA synthetases, a family of enzymes that catalyze a key step in protein synthesis. Co. is developing its development candidate, Resolaris, as an intravenous protein therapeutic for the treatment of rare myopathies with an immune component.